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5 Weird Things We Figured Out On the ISS

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0:00The International Space Station,  
0:01or ISS, has been swinging above humanity’s  collective heads for almost three decades.
0:08But it won’t be up there forever.
0:09Details are still a little vague,  but we’re all going to have to say
0:12Goodbye to the ISS sometime around 2030.
0:16Personally, I will be buying a fifth  of bourbon and trying not to cry
0:20as the remnants of its metallic corpse crash into
0:24Earth’s spaceship graveyard in the South Pacific.
0:26But if the bourbon can’t console me,
0:28I can always think of all the weird  things the ISS taught us about reality.
0:33It turns out a lot of things don’t work  the same up there as they do on Earth.
0:38From human cells, to spiders, to  goodness gracious small balls of fire…
0:43because safety first, people!
0:45So let’s break down five of the weirdest  discoveries we’ve made thanks to the ISS.
0:50[♪ INTRO]
0:53Scientists have a particular interest  in knowing what kinds of life
0:57can and can’t survive outer space environments.
1:00Horror movies are, sadly, not a reliable resource.
1:04For example, they might focus  entirely on the lack of air
1:07or the extreme temperatures, and not at all on the
1:10cancer-causing radiation  that isn’t getting blocked.
1:13If humanity ever wants to try setting  up a colony somewhere as inhospitable
1:17as Mars…let alone terraforming it…we’re  gonna need to know where to start.
1:22Which kinds of life will have  the best chance of survival,
1:25to help give us the best chance?
1:27Well, in a study published in 2025,  one research team attempted to
1:31answer this question by slapping a  bunch of moss to the outside of the ISS.
1:36I’m only kind of exaggerating.
1:38The team chose the species Physcomitrium patens,
1:42which is a cute little  kinda-palm-tree-looking plant
1:45that is used quite a bit  for scientific experiments.
1:48It’s physiologically simple.
1:49We’ve sequenced its full genome.
1:51It’s known to be pretty dang good at  dealing with environmental stress.
1:56What’s not to like?
1:56The team also chose to investigate  three different forms of the moss,
2:00representing three different life stages.
2:03First, there’s protonemata,  which are chains of cells from
2:06very early in the reproductive process.
2:09Then, brood cells, which act like spores.
2:12And finally, sporophytes:  reproductive structures that basically
2:17“give birth” to spores.
2:18All these mossy cells were placed in a small,
2:21box-like container with a  mesh window for exposure,
2:25and attached to a special platform  outside the station’s module called KIBO.
2:30Not with a spacewalk, but with  the space station’s robot arm!
2:34Then, they were left out in space for nine months.
2:37Different samples were  subjected to different aspects
2:40of a standard space environment…  like the general vacuum of it all,
2:44the extreme heat and cold, and perhaps most  damaging of all: ultraviolet radiation.
2:50And while neither the protonemata nor the  brood cells survived the full experiment,
2:55a significant number of the sporophytes did.
2:58A full 99% survived the vacuum of  space, 81% survived the freezing cold,
3:0336% survived the high heat, and 27%  survived the ultra-damaging UV-C rays.
3:11You can’t even get UV-C rays  down on Earth’s surface.
3:15They’re the ones our atmosphere blocks out.
3:17Which is why your sunscreen only  worries about the A and B types.
3:21But that’s not all.
3:22After the surviving sporophytes  were brought back to Earth,
3:2580% of the spores cocooned inside them germinated.
3:30Not only did they live, they lived  enough to carry on a new generation!
3:34Now, granted, even multiple generations of moss
3:37aren’t the most complex life forms in the world.
3:40They’re not even the most complex  plants we’ve brought to space.
3:43In fact, humanity’s done a lot  of research on plants in space.
3:47It’s mostly crop plants, because if we ever  intend to live anywhere other than Earth,
3:51or take really long space journeys,  we’ll need crops to feed ourselves.
3:56But because of their simplicity,  mosses can help scientists set
3:59a solid baseline for how plants in general  may fare in a spaceship’s tiny garden…
4:05or on the surface of another planet.
4:07Certain mosses are also  quite hearty here on Earth,
4:10so they have the potential to  survive in more hostile environments
4:13than complex plants like crops and trees.
4:16So if we can’t get a crop growing on  our first fancy lunar research base,
4:21we could at least ship some  moss up to help make oxygen.
4:24But even if we never wind up  colonizing the solar system,
4:27this research isn’t useless.
4:29Testing plants’ hardiness in space  can help researchers figure out
4:32how resistant they can be to the  effects of climate change on Earth…
4:37which you may have noticed  has become a bit of a problem.
4:41So wherever future humans have to live,
4:43today’s space moss can teach us how to  survive whatever tomorrow’s deal is.
4:48Unless tomorrow reveals we’re  living in a horror movie,
4:52and the monster is space-mutated moss.
4:55Stem cells are the building blocks and  maintenance crews of almost all our tissues.
4:59Not only are they great at  making more of themselves,
5:02but they basically start as blank slates.
5:05Then when given the right chemical signal…BAM!
5:08They transform into a new,  more specialized type of cell.
5:11If scientists can harness that  power for medical treatments…
5:14say, to regrow a patient’s damaged organ…
5:17we could have an absolute  game changer on our hands.  
5:20Now, the stem cells inside of you right now aren’t
5:22as blank slate-y as you’d find in a newborn baby.
5:25After all, the latter ones just got  done cooking, metaphorically speaking.
5:30For example, a newborn’s cardiovascular  progenitor cells, or CPCs,
5:35can create a greater variety of  cardiovascular cells than adult CPCs.
5:40But what if we could convince  those adult CPCs to dream bigger?
5:45Not necessarily all the way to the  true blank slates you find in embryos…
5:49which have to build a body from scratch…
5:52but at least regain the  options of a newborn’s CPCs?
5:55Space could help with that.
5:57According to a paper published in 2021,  if you bring adult CPCs to the ISS,
6:02and let them chill in microgravity for a month,
6:05they will change to resemble something  closer to that newborn state.
6:10Thanks to all kinds of pathways for  chemical reactions and signals opening up,
6:14the cells got even better  at replicating themselves
6:17and differentiating into  other cardiovascular tissues.
6:21One might say the stem cells got even stemmier.
6:25Now, do we know for sure why this happened?
6:28Unfortunately no.
6:29Scientists have a few ideas,  and they observed some
6:32related genes getting turned on and off.
6:34But there’s no concrete answer yet.
6:37We also don’t know how to replicate this on Earth,
6:39to bring about a revolution  in stem cell treatments.
6:43But maybe, if scientists can figure out  what exactly makes those genes flip on and
6:47off, they could make progress on growing  replacement organs from cell cultures.
6:52After all, it’d be great  to circumvent the crucial,
6:55but frustrating bottleneck that is organ donation.
6:59If this study is the first  step, we’ll be on a path to
7:02sci-fi space organ replacements in no time.
7:05Now just like the ISS, SciShow  needs funding to keep running.
7:09So here’s a quick ad.
7:11If you’re still watching, you’re  probably the kind of person
7:13who loves engaging with new ideas  and learning outside of a classroom.
7:17That’s what we offer at SciShow,  and it’s what Brilliant offers too!
7:20You can enjoy all the good  edu-tainment that you get from
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7:43Brilliant’s also given our viewers 20%  off an annual Premium subscription,
7:47which gives you unlimited daily  access to everything on Brilliant.
7:52You’ve probably heard of the three main  states of matter: solid, liquid, and gas.
7:56You’ve also likely heard  of a fourth state: plasma.
7:59The Sun kind, not the blood kind.
8:01But scientists have identified  way more states than four.
8:05Including Bose-Einstein condensates, or BECs.
8:09A BEC emerges when some gas gets so cold,
8:13the weirdness of quantum physics starts  playing out on macroscopic scales.
8:18What do I mean by that?
8:19Well, in quantum physics, each  particle has its own quantum state,
8:23which has nothing to do with the states of matter.
8:25Basically, a particle’s quantum  state is a complex math equation
8:29that describes everything about that  particle, like its position and its spin.
8:34Meanwhile, all particles of the same  type…such as every single electron…
8:38are interchangeable with one another.
8:41So if you collect a bunch of the same  particles that are also sharing the same state,
8:46they’ll wind up amplifying the  quantum behaviors of just one of them.
8:50In a BEC, instead of thousands of separate atoms,
8:53they all collectively act like one large atom.
8:57And scientists can use them to observe  some weird fundamentals of reality,
9:01like how each bit of matter  is both a particle and a wave.
9:06But creating and maintaining a  BEC is easier said than done.
9:10For one thing, when I said “cold”, I meant
9:12“hovering just above absolute zero,”  which is tricky to achieve on Earth.
9:17For another, after you’ve got your BEC,  one standard experiment requires you to
9:21then monitor its particles during free fall.
9:24And when you’re in a lab on Earth,
9:26you’ve got like 1 second of observation time, max.
9:30Lucky for scientists, the ISS  has the Cold Atom Lab onboard,
9:34which solves both those problems.
9:36The Cold Atom Lab is sometimes called  the “coldest spot in the universe”.
9:40And it’s a multi-step process to get it that way.
9:43It starts with laser cooling:  trapping atoms in the middle of
9:47six lasers until they stop vibrating so much.
9:50It’s kind of like how if you push  a kid on a swing at the wrong time,
9:54they’ll slow down instead of picking up speed.
9:58Then, the lab switches off the  lasers and turns on a magnetic trap
10:02to hold the newly chilled atoms,  which is carefully tuned to
10:06allow the hottest of those  uber-cold atoms to evaporate away.
10:10Finally, it turns down the  intensity of the magnetic trap,
10:13and allows the atoms to spread  out and get even colder.
10:17In the microgravity environment of the ISS,
10:20scientists can push this  further than they can on Earth.
10:24They can cool things down to less  than one billionth of one Kelvin…
10:29all from the remote comfort of NASA’s
10:31Jet Propulsion Laboratory in Pasadena, California.
10:35Meanwhile, microgravity also helps  the atoms to stay in free fall longer,
10:40giving scientists much more  time to study their behavior.
10:43We don’t just want to study BECs to better
10:45understand quantum shenanigans, of course.
10:48There are potential practical applications, too.
10:51Like inside superconductors that  transmit electricity without energy loss,
10:55or the lasers in atomic  clocks that keep everything
10:58from the clocks on your phones  to GPS working properly.
11:03But for even more shenanigans,
11:04let’s move on to our next subject of  scientific investigation: spiders.
11:09You may personally have issues with spiders,
11:11but I think they’re cool even when they  aren’t giving teenagers superpowers.
11:15And just like Spider-Man in  1972’s Marvel Team-Up #54,
11:20several real spiders have  been launched into space.
11:23Technically, the bad guys were  trying to launch the Hulk into space,
11:26and Spidey was just there to stop them.
11:28Don’t worry; he got rescued, eventually.
11:31For a long time, scientists  have known that spiders
11:33decide how to orient their webs using gravity.
11:36But they wanted to test if gravity  was the only guide they used.
11:40Hence, the sending of spiders to a space station.
11:43Which, much like studying a  BEC, is easier said than done.
11:48The first spider astronauts arrived  at NASA’s Skylab station back in 1973.
11:53But someone forgot to pack  any food for the spiders,
11:56so the human astronauts couldn't  tell if the weirdly shaped webs
12:00were because the spiders were in  microgravity, or just starving.
12:04Researchers tried again in 2008,  bringing two spiders to the ISS.
12:09The experiment featured one adult  spider and a juvenile backup,
12:13along with colonies of fruit  flies for them to munch on.
12:17Unfortunately, the backup  spider somehow escaped its cell,
12:20and joined the first spider so no  one could tell whose web was whose.
12:24Not that it even mattered, because the  fruit flies wound up reproducing so fast,
12:29the sheer mass of them blocked  the view inside the cell.
12:33But finally, in 2011, scientists  got their spider experiment to work.
12:38They took two golden silk orb weavers to the ISS,
12:42leaving two more on Earth as controls.
12:44The species they picked is  known to make asymmetric webs,
12:48which would make it easier to notice  any differences in orientation.
12:51By the way, the astronauts who  took care of the two spiders
12:54nicknamed them “Esmeralda” and “Gladys.”
12:57The experiment setup was improved to avoid
12:59both cross contamination and fruit fly overload.
13:03And after a 2-month observation  period…and 56 space-based webs…
13:08the team learned that in the absence of gravity,
13:11spiders will use light to orient  both their webs and themselves.
13:16The spiders seemed to treat the direction  of light as “up” and the other as “down,”
13:21implying they instinctively  knew that light meant “up.”
13:25While it might sound weird for spiders to  have a Plan B for when gravity seemingly
13:29disappears, remember that bodies are  fallible…be they human or spider bodies.
13:35It makes sense they evolved another  system that can take over if the
13:38gravity-sensing one fails, or to  work in tandem for extra support.
13:43However, a whopping two space-faring  spiders is a pretty small sample size.
13:48We’ll need a lot more if we want to  make certain this is a real “thing”...
13:52and not just an Esmeralda and Gladys thing.
13:55To be fair, pretty much everything  acts weird in microgravity.
13:59Including fire. Which apparently burns cold.
14:03In a 2012 experiment called FLEX, astronauts set
14:06small droplets of heptane fuel on  fire and let them burn themselves out.
14:11The goal was to better understand  how to extinguish fires,
14:14and they chose heptane because:  1) it’s relatively simple,
14:182) it’s very well-studied,  and 3), at least for a while,
14:22scientists thought it may have been  a good ingredient in some kind of
14:25substitute…or “surrogate”, to use the  technical jargon... for gas or diesel fuel.
14:31How this work will transfer  to other fuels, we don’t know.
14:34But you gotta start somewhere.
14:36During the experiment, the crew saw  the burn, and then saw the extinction…
14:40but their instruments revealed  there was an invisible flame
14:43that kept going until it  finally snuffed itself out.
14:47It turns out, the camera was  capturing a kind of burning
14:50known as cool-flame chemical heat release.
14:53Which isn’t really that cool  from a human perspective.
14:56A cool flame burns around 600 degrees Celsius,
14:59but that’s nowhere near the roughly  2000 degrees you can measure in a flame
15:04burning your typical hydrocarbon fuel.
15:07Under ideal conditions, at least.
15:08While scientists knew heptane  could produce a cool flame before
15:12the much hotter visible flame, getting  one after was a complete shock.
15:17This sparked a whole bunch of excitement  around space-based cool flames,
15:21and in 2021, researchers  were able to get a gas-fueled
15:25cold flame to burn in space for the first time.
15:29One day, cold-flame research  could lead to more efficient and
15:32less polluting engines, turning the  same amount of fuel into more power.
15:37And of course, understanding  how fuel is secretly burning
15:40will keep astronauts safer, as fires  can get very dangerous very quickly
15:45in the tight quarters of a space station  floating in an empty sea of death.
15:50With so much weird and wonderful  science coming from the ISS,
15:54it's a bummer that we have to  say goodbye to it in a few years.
15:58But there's still plenty of time for  scientists to make even weirder discoveries.
16:03[♪ OUTRO]